Orthomolecular Medicine News Service, Feb 21, 2020
Three Intravenous Vitamin C Research Studies Approved for Treating COVID-19
by Andrew W. Saul, Editor
(OMNS February 21, 2020) Intravenous vitamin C is already being employed in China against COVID-19 coronavirus. I am receiving regular updates because I am part of the Medical and Scientific Advisory Board to the International Intravenous Vitamin C China Epidemic Medical Support Team.
Its director is Richard Z. Cheng, MD, PhD; associate director is Hong Zhang, PhD. Among other team members are Qi Chen, PhD (Associate Professor, Kansas University Medical School); Jeanne Drisko, MD (Professor, University of Kansas Medical School); Thomas E. Levy, MD, JD; and Atsuo Yanagisawa, MD, PhD. (Professor, Kyorin University, Tokyo).
To read the treatment protocol information in English:
http://orthomolecular.org/resources/omns/v16n07.shtml
Protocol in Chinese at
http://www.doctoryourself.com/Coronavirus_Chinese_IV_C_Protocol.pdf
To read the treatment protocol information in English:
http://orthomolecular.org/resources/omns/v16n07.shtml
Protocol in Chinese at
http://www.doctoryourself.com/Coronavirus_Chinese_IV_C_Protocol.pdf
China Epidemic Medical Support Team
http://www.drwlc.com/blog/2010/07/29/about-dr-richard-cheng/
http://www.drwlc.com/blog/2010/07/29/about-dr-richard-cheng/
Direct report from China
OMNS Chinese edition editor Dr. Richard Cheng is reporting from China about the first approved study of 12,000 to 24,000 mg/day of vitamin C by IV. The doctor also specifically calls for immediate use of vitamin C for prevention of coronavirus (COVID-19).
A second clinical trial of intravenous vitamin C was announced in China on Feb. 13th. In this second study, says Dr. Cheng, "They plan to give 6,000 mg/day and 12,000 mg/day per day for moderate and severe cases. We are also communicating with other hospitals about starting more intravenous vitamin C clinical studies. We would like to see oral vitamin C included in these studies, as the oral forms can be applied to more patients and at home."
Additional information at http://orthomolecular.org/resources/omns/v16n11.shtml
And on Feb 21, 2020, announcement has been made of a third research trial now approved for intravenous vitamin C for COVID-19. https://www.youtube.com/watch?v=VMDX0RSDp1k&feature=youtu.be
Dr. Cheng, who is a US board-certified specialist in anti-aging medicine, adds:
"Vitamin C is very promising for prevention, and especially important to treat dying patients when there is no better treatment. Over 2,000 people have died of the COIV-19 outbreak and yet I have not seen or heard large dose intravenous vitamin C being used in any of the cases. The current sole focus on vaccine and specific antiviral drugs for epidemics is misplaced."
He adds that: "Early and sufficiently large doses of intravenous vitamin C are critical. Vitamin C is not only a prototypical antioxidant, but also involved in virus killing and prevention of viral replication. The significance of large dose intravenous vitamin C is not just at antiviral level. It is acute respiratory distress syndrome (ARDS) that kills most people from coronaviral pandemics (SARS, MERS and now NCP). ARDS is a common final pathway leading to death.
"We therefore call for a worldwide discussion and debate on this topic."
News of vitamin C research for COVID-19 is being actively suppressed
Indeed, the World Health Organization (WHO) has, literally, met with Google and Facebook and other media giants to stop the spread of what they declare to be wrong information.
https://www.cnbc.com/amp/2020/02/14/facebook-google-amazon-met-with-who-to-talk-coronavirus-misinformation.html?__twitter_impression=true
https://www.cnbc.com/amp/2020/02/14/facebook-google-amazon-met-with-who-to-talk-coronavirus-misinformation.html?__twitter_impression=true
Physician-directed, hospital-based administration of intravenous vitamin C has been marginalized or discredited. Scientific debate over COVID-19 appears to not be allowed.
Ironically, Facebook, blocking any significant users' sharing of the news of approved vitamin therapy research, is itself blocked in China by the Chinese government. As for the internet, yes, China has it. And yes, it is censored. But, significantly, the Chinese government has not blocked this real news on how intravenous vitamin C will save lives in the COVID-19 epidemic. Here is the protocol as published in Chinese: http://orthomolecular.org/resources/omns/v16n11-chi.shtml
Medical orthodoxy obsessively focuses on searching for a vaccine and/or drug for coronavirus COVID-19). While they are looking for what would be fabulously profitable approaches, we have with vitamin C an existing, plausible, clinically demonstrated method to treat what coronavirus patients die from: severe acute respiratory syndrome, or pneumonia.
And it is available right now.
To read all Orthomolecular Medicine News Service Reports on COVID coronavirus and intravenous vitamin C:
| Vol. 16, No. 04 | January 26, 2020 | Vitamin C Protects Against Coronavirus |
| Vol. 16, No. 06 | January 30, 2020 | Nutritional Treatment of Coronavirus |
| Vol. 16, No. 07 | February 2, 2020 | Hospital-based Intravenous Vitamin C Treatment for Coronavirus and Related Illnesses |
| Vol. 16, No. 09 | February 10, 2020 | VITAMIN C AND ITS APPLICATION TO THE TREATMENT OF nCoV CORONAVIRUS: How Vitamin C Reduces Severity and Deaths from Serious Viral Respiratory Diseases |
| Vol. 16, No. 10 | February 13, 2020 | Coronavirus Patients in China to be Treated with High-Dose Vitamin C |
| Vol. 16, No. 11 | February 16, 2020 | Early Large Dose Intravenous Vitamin C is the Treatment of Choice for 2019-nCov Pneumonia |
Nutritional Medicine is Orthomolecular Medicine
Orthomolecular medicine uses safe, effective nutritional therapy to fight illness. For more information: http://www.orthomolecular.org
Find a Doctor
To locate an orthomolecular physician near you: http://orthomolecular.org/resources/omns/v06n09.shtml
The peer-reviewed Orthomolecular Medicine News Service is a non-profit and non-commercial informational resource.
___MORE:
Vitamin C Protects Against Coronavirus
"Some physicians would stand by and see their patient die rather than use ascorbic acid (Vitamin C) because in their finite minds it exists only as a vitamin."
VITAMIN C HAS BEEN KNOWN TO CURE OVER 30 MAJOR DISEASES FOR OVER 70 YEARS
- If so, why haven't you heard more about it?
- Why haven't more doctors used Vitamin C as medicine?
Progress takes time, unfortunately. Fresh fruit was known to cure scurvy by 1753, yet governments ignored the fact for nearly 100 years.
- Why haven't more doctors used Vitamin C as medicine?
Progress takes time, unfortunately. Fresh fruit was known to cure scurvy by 1753, yet governments ignored the fact for nearly 100 years.
Countless thousands died in the meantime. The 19th century doctor who first advocated washing one's hands between patients died ignored and in disgrace with the medical profession. Toxic mercury was used as medicine into the twentieth century. And so it has been.
The first physician to aggressively use vitamin C to cure diseases was Frederick R. Klenner, M.D. beginning back in the early 1940's.
Dr. Klenner consistently cured chicken pox, measles, mumps, tetanus and polio with huge doses of the vitamin. While vaccines are now available for these illnesses, please remember this was not the case in the 1940's.
The following is a list of the conditions that Dr. Klenner successfully treated with aggressive vitamin C therapy:
Pneumonia
Encephalitis
Herpes Zoster (shingles)
Herpes Simplex
Mononucleosis
Pancreatitis
Hepatitis
Rocky Mountain Spotted Fever
Bladder Infection
Alcoholism
Arthritis
Some Cancers
Leukemia
Atherosclerosis
Intervertebral Disc
High Cholesterol
Corneal Ulcer
Diabetes
Glaucoma
Schizophrenia
Burns and secondary infections
Heat Stroke
Radiation Burns
Heavy Metal Poisoning (Mercury, Lead), Venomous Bites (insects, snakes), Multiple Sclerosis, Chronic Fatigue, Complications of Surgery
This seems like an impossible list of vitamin C cures. At this point, you can either dismiss the subject or investigate further. Dr. Klenner chose to investigate.
The result?
He used massive doses of vitamin C for over forty years of family practice. He wrote dozens of medical papers on the subject. A complete list of them is in the Clinical Guide to the Use of Vitamin C, edited by Lendon H. Smith, M.D., Life Sciences Press, Tacoma, WA (1988).
Dr. Klenner consistently cured chicken pox, measles, mumps, tetanus and polio with huge doses of the vitamin. While vaccines are now available for these illnesses, please remember this was not the case in the 1940's.
The following is a list of the conditions that Dr. Klenner successfully treated with aggressive vitamin C therapy:
Pneumonia
Encephalitis
Herpes Zoster (shingles)
Mononucleosis
Pancreatitis
Hepatitis
Rocky Mountain Spotted Fever
Bladder Infection
Alcoholism
Arthritis
Some Cancers
Leukemia
Atherosclerosis
Intervertebral Disc
High Cholesterol
Corneal Ulcer
Diabetes
Glaucoma
Schizophrenia
Burns and secondary infections
Heat Stroke
Radiation Burns
Heavy Metal Poisoning (Mercury, Lead), Venomous Bites (insects, snakes), Multiple Sclerosis, Chronic Fatigue, Complications of Surgery
This seems like an impossible list of vitamin C cures. At this point, you can either dismiss the subject or investigate further. Dr. Klenner chose to investigate.
The result?
He used massive doses of vitamin C for over forty years of family practice. He wrote dozens of medical papers on the subject. A complete list of them is in the Clinical Guide to the Use of Vitamin C, edited by Lendon H. Smith, M.D., Life Sciences Press, Tacoma, WA (1988).
It is difficult to ignore his success, but it has been done.
Dr. Klenner wrote: "Some physicians would stand by and see their patient die rather than use ascorbic acid (Vitamin C) because in their finite minds it exists only as a vitamin."
Vitamin C is remarkably safe even in enormously high doses. Compared to commonly used prescription drugs, side effects are virtually nonexistent. It does not cause kidney stones. In fact, vitamin C increases urine flow and favorably lowers the pH to help keep stones from forming. William J. McCormick, M.D. used vitamin C since the late 1940's to prevent and treat kidney stones. Vitamin C does not significantly raise oxalate levels, and uric acid stones have never resulted from its use, either.
Said Dr. Klenner: "The ascorbic acid/kidney stone story is a myth."
How much vitamin C is an effective therapeutic dose? Dr. Klenner gave up to 300,000 milligrams (mg) per day.
Generally, he gave 350 to 700 mg per kilogram body weight per day. That is a lot of Vitamin C.
But then again, look at that list of successes.
Dr. Klenner emphasized that small amounts do not work.
He said, "If you want results, use adequate ascorbic acid (Vitamin C)." https://graviolateam.blogspot.com/2020/02/vitamin-c-protects-against-coronavirus.html
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The Corona virus can be destroyed naturally?
Why is vitamin C so effective in killing viruses?
A primary way in which vitamin C destroys viruses, or sets them up for destruction by the immune system, is by activating the ‘Fenton reaction’.In a nutshell, this reaction can proceed inside the virus, inside cells in which viruses are replicating, and on the surfaces of the viruses themselves. The result of this reaction that is stimulated by the presence of vitamin C, one or more transition metal cations, and the local presence of peroxide is the immediate production of hydroxyl radicals. These radicals are the most reactive oxidizing agents ever identified.
As such, they radically upregulate oxidative stress and end up destroying whatever is in their immediate environment.
https://graviolateam.blogspot.com/2020/01/the-corona-virus-can-be-destroyed.html
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Yet More Evidence for IV Vitamin C
On Tuesday, April, 4th, 2017 in IV Drip Therapy No Comments
There’s yet another study we can add to those we blogged about earlier this year, research showing how IV vitamin C can deliver big benefits in a variety of health situations.
A new study in Chest provides good evidence that an IV cocktail of vitamin C, thiamine (vitamin B1), and hydrocortisone may be extraordinarily effective for treating sepsis – a deadly condition that occurs when the body’s response to an infection damages its own organs.
The study compared the clinical outcomes of 47 septic patients treated with this cocktail during a 7-month period with those of 47 septic ICU patients treated conventionally before the study began.
https://graviolat.blogspot.com/2020/02/evidence-for-iv-vitamin-c.html___
THE FENTON REACTION: pro-oxydant role of vitamin C
- THE DOUBLE FACED CHARACTER OF VITAMIN C
- THE FENTON REACTION
- ASCORBIC ACID AND THE FENTON REACTION
- VITAMIN C PRO-OXYDANT ACTIVITY DAMAGE
- ASCORBIC ACID AND ITS PRO OXIDANT ACTIVITY AS A THERAPY
THE FENTON REACTION: pro-oxydant role of vitamin C
ROS (Reactive Oxygen Species)
cristina ghia | 04/06/2014
More than eighty years since its discovery, the understanding of the functions of ascorbic acid has evolved from the prevention of scurvy to its potential use as a therapeutic drug for cancer treatment.
Ascorbate maintains Fe2+ of collagen hydroxylases in an active state; therefore it plays a pivotal role in collagen synthesis; parallel reactions with a variety of dioxygenases affect the expression of a wide array of genes, for example via the HIF system, and possibly the epigenetic landscape of cells and tissues.
The ability to donate one or two electrons makes ascorbate an excellent reducing agent and antioxidant.
However, in the presence of catalytic metals, ascorbate also has pro-oxidant effects, where the redox-active metal is reduced by ascorbate and then in turn reacts with oxygen, producing superoxide that subsequently dismutes to produce H2O2.
Ascorbic acid or Vitamin C is a potent dietary antioxidant with a double faced character, in that it exhibits a pro-oxidant activity arising from its routine antioxidant property that generates reactive free radicals.
Vitamin C has antioxidant activity when it reduces oxidizing substances such as hydrogen peroxide, however, it can also reduce metal ions which leads to the generation of free radicals.
The metal ion in this reaction can be reduced, oxidized, and then re-reduced, in a process called redox cycling that can generate reactive oxygen species.
https://graviolat.blogspot.com/2020/02/the-fenton-reaction-pro-oxydant-role-of.html
______
Valeria Ceolin
Cristina Ghia
Cristina Ghia
INTRODUCTION
Ascorbate maintains Fe2+ of collagen hydroxylases in an active state; therefore it plays a pivotal role in collagen synthesis; parallel reactions with a variety of dioxygenases affect the expression of a wide array of genes, for example via the HIF system, and possibly the epigenetic landscape of cells and tissues.
The ability to donate one or two electrons makes ascorbate an excellent reducing agent and antioxidant.
However, in the presence of catalytic metals, ascorbate also has pro-oxidant effects, where the redox-active metal is reduced by ascorbate and then in turn reacts with oxygen, producing superoxide that subsequently dismutes to produce H2O2.
ASCORBIC ACID AND THE FENTON REACTION
Ascorbic acid can recycle Fe(III) to Fe(II) facilitating further generation of reactive oxygen species by subsequent Fenton cycles.
- 2 Fe2+ + 2 H2O2 → 2 Fe3+ + 2 OH• + 2 OH−
- 2 Fe3+ + Ascorbate → 2 Fe2+ + Dehydroascorbate
THE DOUBLE FACED CHARACTER OF VITAMIN C
Ascorbic acid or Vitamin C is a potent dietary antioxidant with a double faced character, in that it exhibits a pro-oxidant activity arising from its routine antioxidant property that generates reactive free radicals.
Vitamin C has antioxidant activity when it reduces oxidizing substances such as hydrogen peroxide, however, it can also reduce metal ions which leads to the generation of free radicals.
The metal ion in this reaction can be reduced, oxidized, and then re-reduced, in a process called redox cycling that can generate reactive oxygen species.
https://graviolat.blogspot.com/2020/02/the-fenton-reaction-pro-oxydant-role-of.html
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